User: liam.philip.shaw

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Posts by liam.philip.shaw

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Comment: C: DESeq with hierarchical FDR correction
... Hi Michael, Thanks for your reply. I had read that section of the vignette and accessed the individual estimates of dispersion and the priors. My question about the 'fit' was because I'm still unclear about how the dispersion prior is used in the fitting - very much not a statistician - but I'll k ...
written 2.3 years ago by liam.philip.shaw0
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DESeq with hierarchical FDR correction
... I've been using DESeq2 in Phyloseq  (see this tutorial) for differential abundance testing in a microbiome data set i.e. OTUs, not genes.   The default multiple testing correction applied in the 'results' function is Benjamini-Hochberg. However, OTUs are not independent. There is information availa ...
deseq2 fdr written 2.3 years ago by liam.philip.shaw0 • updated 2.3 years ago by Michael Love14k

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