Hi

I have column of gene expression  of 208 (104X2) samples. I want to take mean of all replicates using R loop Can any one suggest me

w x y a b e

5 1 1 2 4 1

6 2 2 5 3 6

7 3 3 8 9 3

8 4 6 9 1 3

so for example i have have w x y a b e columns i want to take avaerage of w and x, y and a , b and e and Print the average value into another data frame names as w_x y_a b_e

The avearrays() function in the limma package does what you want. For example, if the replicates you want to average are side by side, then

ID <- rep(1:104, each=2)
ReducedExprMatrix <- avearrays(ExprMatrix, ID)

In general, columns with the same ID will be averaged.