Question: EstimateDisp and glm
0
gravatar for samoura48
4 weeks ago by
samoura480
samoura480 wrote:

Hello,

I am new in R. I want to identify genes differentially expressed by using GLM. I used the function model.matrix to get the design matrix and then wanted to estimate the dispersion using the function estimateDisp ( Actually it was my professor's solution). I didn't understand what does estimateDisp do exactly? Thank you for your answer

edger • 109 views
ADD COMMENTlink modified 4 weeks ago by Aaron Lun22k • written 4 weeks ago by samoura480
Answer: EstimateDisp and glm
0
gravatar for Aaron Lun
4 weeks ago by
Aaron Lun22k
Cambridge, United Kingdom
Aaron Lun22k wrote:

Try reading:

  • ?estimateDisp
  • The dispersion estimation section of the workflow.
  • Section 2.10.2 of the edgeR user's guide.
  • The relevant paper.

If you still don't get it, you should probably discuss your difficulties with your professor (it's their job, after all) before asking random strangers on the internet. 

ADD COMMENTlink modified 4 weeks ago • written 4 weeks ago by Aaron Lun22k

Thank you.

 

ADD REPLYlink written 4 weeks ago by samoura480
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