OVERVIEW:

In MCCB of University of Massachusetts Medical School, we have developed a core team of accomplished computational biologists who work side-by-side with bench scientists to evaluate, select and develop algorithms and software pipelines to analyze, annotate, visualize and integrate various biological datasets, including those generated from high-throughput experiments such as ChIP-seq, RNA-seq, PAS-seq, ATAC-Seq, miRNA-seq, exon sequencing, GUIDE-seq, single-cell sequencing, NAD-Seq, PAS-Seq, shRNA and gRNA screening, and CRISPR genome editing. We are active contributors to the open-source open-development Bioconductor project. We have developed more than a dozen packages with various utilities, ranging from machine learning, peak calling, annotation, visualization, to gRNA design and evaluation.

GENERAL SUMMARY OF POSITION:

Under the general direction of the bioinformatics core director, the senior Bioinformatician is responsible for developing novel algorithms and developing/enhancing/maintaining scientific software applications as well as providing bioinformatics data analysis support for various research projects.

MAJOR RESPONSIBILITIES:

• Develop novel algorithms and software tools for integrated data analysis and visualization of high-throughput dataset including next-generation sequencing data and proteomics data when existing software packages are not available or adequate
• Enhance/Maintain Bioconductor packages developed in house
• Collaborate closely with PIs and their lab members on research projects including evaluating, selecting, and implementing when needed the best of breed computational solutions for the analysis of biological data
• Develop rapid prototypes and custom scripts for one-off type of analysis requests
• Properly document the procedures used in computational analysis and provide summary report of results suitable for inclusion in manuscript and grant applications
• Participate in the oral presentation of all project findings and abstracts including participation in periodic project status meetings and presentation of final project deliverables.
• Local establishment and customization of genomic, proteomics databases and provide batch analysis utilities that make use of these resources
• Develop custom databases and web portals for managing raw and processed experimental data if needed
• Provide bioinformatics training and workshops for analysis pipelines and in-house developed software applications
• Coordinate and collaborate with other bioinformaticians, biostatisticians, information technology professionals, and interdepartmental project teams
• Perform other duties as required

REQUIRED QUALIFICATIONS:

• Master's degree in Bioinformatics, Computer Science, Statistics or related computational disciplines
• Minimum 3 year bioinformatics-related research experience
• Proven research record such as co-authorship on peer-reviewed publications required
• Strong background in programming. Fluent in one programming language (Java or C/C++) and one scripting language (shell, Perl or Python)
• Knowledge in biostatistics packages (R or Matlab) and SQL queries are strongly suggested
• Strong communication skills, both the oral and written necessary to interact with a wide range of individuals

PREFERRED QUALIFICATIONS:

• PhD degree in Bioinformatics, Computer Science, Statistics or related discipline preferred
• R/Bioconductor package developer/maintainer/Users preferred
• Algorithm development experience preferred
• Software development experience preferred
• Experience running computational methods/pipelines in high performance computing clusters preferred

Interested applicants are invited to apply at https://www.ummsjobs.com/job/4222/, https://www.ummsjobs.com/job/4223/, and https://www.ummsjobs.com/job/4507/.

Additional Information: Why Join UMass Medical School? The University of Massachusetts Medical School (UMMS) offers a very competitive compensation and benefits package including four weeks paid vacation, free tuition at any Massachusetts state school, a robust and affordable variety of health and dental plans, participation in the state retirement plan, and a rewarding environment driven by distinctive work in progressive education and research.

If challenging and competitive work in a fast paced environment appeal to you, consider sharing your talents with one of the fastest growing academic health centers in the country.

Ranked 7th in primary-care education and 48th in research among the United States' 125 medical schools in the 2012 .S. News & World Report annual guide, "America’s Best Graduate Schools,” UMMS is also a world recognized research center. Beyond its core mission of distinction in health sciences education, UMMS has exploded onto the national and international scene as a major center for research with UMMS researchers making pivotal advances in HIV, cancer, diabetes, genetic disorders, infectious disease and in understanding the molecular basis of disease.