Is it possible to run diffbind with my "own" binding affinity table? I might want to delete certain peaks or have my own way of combining peaks across replicates.
Let's say I have a table
mytable.tsv that looks like this:
sample1 sample2 sample3 peak1 312 366 12 peak2 999 12 512 peak3 2 521 52
If so, should I then still do e.g. TMM normalization afterward? Or should I load a TMM (or whatever normalization I want) normalized table?