retrieving specific FDR value from SAM
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Alex Tsoi ▴ 260
@alex-tsoi-2154
Last seen 9.7 years ago
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@holger-schwender-344
Last seen 9.7 years ago
Hi, with the current release version (1.10.1) of siggenes, you have to try several delta values to find the delta value that leads to a specific FDR. However, I have currently implemented a function called findDelta which is available in siggenes 1.11.10 and later (you can download this version from the developmental branch of Bioconductor) that exactly does what you want: E.g., > findDelta(sam.out, 0.2) gives you the delta value and the number of genes called significant if the FDR should be 0.2. Best, Holger -------- Original-Nachricht -------- Datum: Tue, 24 Jul 2007 11:50:57 -0400 Von: "Alex Tsoi" <tsoi.teen at="" gmail.com=""> An: bioconductor at stat.math.ethz.ch Betreff: [BioC] retrieving specific FDR value from SAM > Dear all, > > > I am working on a meta microarray analysis, and I have + 10 SAM output > (the > sam() results). For each of the output, I would like to get the delta > value > that is corresponding to a specific FDR (eg. 0.2), and use the delta value > to get the summary of the sam for retrieveing the differentially expressed > genes. Could any of you show me how to automatically get the delta value > that is corresponding to a specific FDR ? > > Many thanks > > -- > Lam C. Tsoi (Alex) > Medical University of South Carolina > > [[alternative HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor --
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