Gene Signature Score Prediction
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affy snp ▴ 640
@affy-snp-2480
Last seen 9.7 years ago
Hi list, I wonder, for gene expression analysis, would it possibe (in the future) , using a bioconductor package, that I supply a list of genes of interest with gene expression values and fold change (condition 1 vs. condition2) and then calculate the scores of this gene signature in each microarray sample? I am not sure the above question has already been asked or solved or in plan, maybe? Thank you very much for your help! Sincerely, Allen [[alternative HTML version deleted]]
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@sean-davis-490
Last seen 4 months ago
United States
On Wed, Jun 4, 2008 at 9:24 PM, ss <affysnp at="" gmail.com=""> wrote: > Hi list, > > I wonder, for gene expression analysis, would it possibe (in the future) , > using a bioconductor package, > that I supply a list of genes of interest with gene expression values and > fold change (condition 1 vs. condition2) > and then calculate the scores of this gene signature in each microarray > sample? This sounds like class prediction. There are numerous methods for doing so in R. I would recommend looking at the MLInterfaces package as a starting place, but there are MANY other methods available. Extensive literature exists on the subject, also. Sean
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