Dear all, I called microRNA package when I tried rtracklayer package on a Mac OS X 10.4 machine. Errors produced when loading the depended package Rlibstree (see below). I tried installed Rlibstree alone from binaries or source, both failed. Error messages (see below). suggested that R_newStringSet and R_stringSetAdd functions (in stree.c file) had problem when passing argument 1 of 'lst_string_new'. This seems to be consistent with the loading error message, but I am not sure what does it mean. Could anybody help or give any hints. Thanks a lot! Weijun #Loading error Loading required package: Rlibstree Error in dyn.load(file, DLLpath = DLLpath, ...) : unable to load shared library '/Library/Frameworks/R.framework/Resou rces/library/Rlibstree/libs/ppc/Rlibstree.so': dlopen(/Library/Frameworks/R.framework/Resources/library/Rlibstree/l ibs/ppc/Rlibstree.so, 6): Symbol not found: _lst_alg_longest_common_substring Referenced from: /Library/Frameworks/R.framework/Resources/library/R libstree/libs/ppc/Rlibstree.so Expected in: dynamic lookup Error: package 'Rlibstree' could not be loaded > sessionInfo() R version 2.8.0 (2008-10-20) powerpc-apple-darwin8.11.1 locale: C attached base packages: [1] tools stats graphics grDevices utils datasets methods [8] base other attached packages: [1] matchprobes_1.14.0 affy_1.20.0 Biobase_2.2.1 loaded via a namespace (and not attached): [1] affyio_1.10.1 preprocessCore_1.4.0 Installing error (from source) ? gcc -arch ppc -std=gnu99 -I/Library/Frameworks/R.framework/Resources/include -I/Library/Frameworks/R.framework/Resources/include/ppc -I../local/include/ -I/usr/local/include -fPIC -g -O2 -c prefix.c -o prefix.o gcc -arch ppc -std=gnu99 -I/Library/Frameworks/R.framework/Resources/include -I/Library/Frameworks/R.framework/Resources/include/ppc -I../local/include/ -I/usr/local/include -fPIC -g -O2 -c stree.c -o stree.o stree.c: In function 'R_newStringSet': stree.c:100: warning: passing argument 1 of 'lst_string_new' discards qualifiers from pointer target type stree.c: In function 'R_stringSetAdd': stree.c:316: warning: passing argument 1 of 'lst_string_new' discards qualifiers from pointer target type gcc -arch ppc -std=gnu99 -dynamiclib -Wl,-headerpad_max_install_names -mmacosx-version-min=10.4 -undefined dynamic_lookup -single_module -multiply_defined suppress -L/usr/local/lib -o Rlibstree.so prefix.o stree.o -L../local/lib -lstree -F/Library/Frameworks/R.framework/.. -framework R -Wl,-framework -Wl,CoreFoundation /usr/bin/libtool: for architecture cputype (16777223) cpusubtype (3) object: /usr/local/lib/libgcc_s.10.4.dylib malformed object (unknown load command 4) make: *** [Rlibstree.so] Error 1 chmod: /Library/Frameworks/R.framework/Versions/2.8/Resources/library/ Rlibstree/libs/ppc/*: No such file or directory ERROR: compilation failed for package 'Rlibstree' ** Removing '/Library/Frameworks/R.framework/Versions/2.8/Resources/li brary/Rlibstree' ** Restoring previous '/Library/Frameworks/R.framework/Versions/2.8/Re sources/library/Rlibstree'