Hi, I have a vector x of length = 2109199 The coordinates are from 50 to 146273025 (approximately every 35bp, but there are some gaps) I set: maxk = 30 maxseg = 140613 = length/15 and run: segs <- segment(x, maxk = maxk, maxseg = maxseg) Here's the error message: Error in .Call("findsegments", G, maxseg, verbose, PACKAGE = "tilingArray") : negative length vectors are not allowed Help anyone? Thanks! -HT [[alternative HTML version deleted]]