To the concerned, I'm into analyzing data derived from MeDIP microarray experiment.This is how my data looks after applying the MEDME package. GeneSymbol    Sample1       Sample2     Sample3     Sample4 P53                    -0.1012           1.018        -0.06311 -0.7823 DNMT               1.1580            0.132        -0.4743 -0.3456 SSH                  -0.0361           -1.678        -0.2404 1.6752 NLG1                -0.0369            0.782         0.3692 0.5431 UNC                   1.1379            1.652        -1.3291 2.4561 I want to further perform ROC ananlysis to the above mentioned data.Could you kindly tell me how to proceed with it so as to obtain appropriate result? Prashantha Hebbar Kiradi, Lecturer, Dept. of Biotechnology, Manipal Life Sciences Center, Manipal University, Manipal, India PIN: 576104 Email:prashantha.hebbar@manipal.edu Phone: +91-9886359007 [[alternative HTML version deleted]]

On Fri, Dec 18, 2009 at 2:42 AM, Prashantha Hebbar <prashantha.hebbar at="" yahoo.com=""> wrote: > To the concerned, > I'm into analyzing data derived from MeDIP microarray experiment.This is how my data looks after applying the MEDME package. > > GeneSymbol??? Sample1?????? Sample2???? Sample3???? Sample4 > P53??????????????????? -0.1012?????????? 1.018??????? -0.06311????? -0.7823 > DNMT?????????????? 1.1580??????????? 0.132??????? -0.4743??????? -0.3456 > SSH????????????????? -0.0361?????????? -1.678??????? -0.2404???????? 1.6752 > NLG1??????????????? -0.0369??????????? 0.782???????? 0.3692???????? 0.5431 > UNC?????????????????? 1.1379??????????? 1.652??????? -1.3291???????? 2.4561 > > > I want to further perform ROC ananlysis to the above mentioned data.Could you kindly tell me how to proceed with it so as to obtain appropriate result? Hello, Prashantha. Have a look at the ROC package in Bioconductor. If you need more help, you'll probably need to be a bit more specific in your question. Sean