Dear Bioconudctor, I have this question about how to compress the gene expression dataset from probe sets denoted to gene denoted values. The analysis has two simultaneous goals, first is to convert the probe sets to gene names. Second is to convert the probe sets values into just one summary gene expression value of the associated gene. For example, we have 21 probes that corresponding to only 4 genes, Is there any package will fulfill the goal of deriving a summary information of a probe set corresponding to a specific gene? Another question is: if there are no gene assignments for our data (only probes names here),is there any way to assign the genes to each probe simultaneous when getting the summary information of the probe set? When download the annotation file. I noticed there are some probes which have two or more gene names, and in such case, we want to have two same columns with different gene names. Thank you so much! Best, Xiaowei [[alternative HTML version deleted]]