Hi, The code snippet in analyseDirectory: storemet<-NULL for(i in fmet){ storemet <- rbind(storemet,read.table(file.path(dir,fileList[i],fsep = .Platform$file.sep),header=T,as.is=T,sep="\t")) fileList <- fileList[-i]; } produces the error: Error in rbind(deparse.level, ...) : numbers of columns of arguments do not match I changed the code to: storemet<-NULL for(i in fmet){ storemet <- rbind(storemet,read.table(file.path(dir,fileList[i],fsep = .Platform$file.sep),header=T,as.is=T,sep="\t")) } fileList <- fileList[-fmet] and this works. Juerg Straubhaar UMASS Med