Question: aCGH segmentation with DNAcopy
gravatar for Emilie Lalonde
6.6 years ago by
Emilie Lalonde10 wrote:
Hello, I'm analyzing some aCGH data (Agilent 244k arrays) using DNAcopy but am confused about one point. When creating the input (CNA object), DNAcopy asks for the chromosome and location of each probe. However, for non-SNP based platforms, how does DNACopy know the size of each probe since it only asks for one position / probe (vs for example providing probe start and end coordinates)? Does DNAcopy assume probes start at the provided position and end at the start of the next probe? Or is this information not relevant to the CBS algorithm? Thank you, emilie [[alternative HTML version deleted]]
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