Dear group Is there a way I can transform any of the three formats ( http://svitsrv25.epfl.ch/R-doc/library/made4/html/NCI60.html) of the expression data of NCI60 cancer cell lines into gene expression status, i.e. I want to identify which genes are up/down/constitutive ? or can we use z-scores to derive such information ? Thanks a lot Alyaa Mahmoud -- Alyaa Mahmoud "Love all, trust a few, do wrong to none"- Shakespeare [[alternative HTML version deleted]]