Question: DESeq2 : when the variable of interest is not a factor

0

Marie Sémon •

**50**wrote:Dear all,
I wish to find genes whose expression profile correlates with a
variable
of interest, which is quantitative (say, the weight of the
individuals).
Is it possible/a good practice to use DESeq2 for this?
One one hand the vignette clearly describes factors (qualitative)
variables, but, on the other hand there is this sentence, p8:
"If the variable of interest is not a factor, the log2 fold change can
be interpreted as the amount of doubling observed on average for every
unit of change."
Many thanks for you help
With kind regards,
Marie

ADD COMMENT
• link
•
modified 4.6 years ago
by
Jose M Garcia Manteiga •

**310**• written 4.6 years ago by Marie Sémon •**50**