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Pedro Madrigal
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20
@pedro-madrigal-6183
Last seen 10.0 years ago
Dear Bioconductor community,
DNase-seq has been used to measure chromatin accessibility in
a given
tissue or cell type on a genome-wide scale. In addition to DNaseI
hypersensitivite sites (DHSs), short regions of protected nucleotides
known as footprints can be detected, indicating transcription factor
binding ocuppancy events.
DNaseR, a new package for DNase I footprinting analysis of
DNase-seq
data will be released in the upcoming version of Bioconductor. Devel
version is
at:Â http://bioconductor.org/packages/2.13/bioc/html/DNaseR.html [1]
DNaseR aims to detect protein binding footprints in DNase-seq
data
from reads in BAM standard aligment format.
Comments are very wellcome.
Best regards,Pedro Madrigal
Research AssociateWellcome Trust Sanger InstituteWellcome Trust Genome
CampusHinxton,Cambridge, CB10 1SAUK
Links:
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[1] http://bioconductor.org/packages/2.13/bioc/html/DNaseR.html
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