Dear Hatice, Thanks for your question about recent updates to the limma package. You can see a description of all recent changes to the package by typing changeLog(100) at the R prompt, where the argument is the number of lines of description that you wish to see. Update to the latest version of limma (3.18.3) if you haven't already. Best wishes Gordon --------------------------------------------- Professor Gordon K Smyth, Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Vic 3052, Australia. http://www.statsci.org/smyth ______________________________________________________________________ The information in this email is confidential and intend...{{dropped:4}}