important bug fix in the package affy
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Laurent Gautier ★ 2.3k
@laurent-gautier-29
Last seen 10.3 years ago
To whom it makes concerned: The released version of the package problem suffered from a rather annoying problem in the method 'computeExprSet'. As a result, the expression values computed have very good chances to be rather incorrect (whatever the method you used). Many thanks to Michael Morley for warning us about strange results compared to MAS5.0 (the bug was found while digging that). I would strongly recommend to re-run expression value computation with the version 1.1.1 of the package (should appear by tomotrrow on the website) if you are currently working with expression data obtained with 1.1. Sorry for the inconvenience. Laurent
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Isaac Neuhaus ▴ 360
@isaac-neuhaus-22
Last seen 9.6 years ago
United States
Laurent: Can you elaborate a bit more? For example, is computeExprSet an internal function used by express or expresso? Isaac Gautier wrote: > To whom it makes concerned: > > The released version of the package problem suffered from a rather annoying > problem in the method 'computeExprSet'. As a result, the expression values > computed have very good chances to be rather incorrect (whatever the method > you used). Many thanks to Michael Morley for warning us about strange results > compared to MAS5.0 (the bug was found while digging that). > I would strongly recommend to re-run expression value computation with > the version 1.1.1 of the package (should appear by tomotrrow on the website) > if you are currently working with expression data obtained with 1.1. > > Sorry for the inconvenience. > > Laurent > > _______________________________________________ > Bioconductor mailing list > Bioconductor@stat.math.ethz.ch > http://www.stat.math.ethz.ch/mailman/listinfo/bioconductor
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On Tue, Dec 03, 2002 at 08:54:13AM -0500, Isaac Neuhaus wrote: > Laurent: > > Can you elaborate a bit more? For example, is computeExprSet an internal > function used by express or expresso? I am afraid it is supposed to be the case... however, it seems that express (that was supposed to have this part of its code based on computeExprSet (*)) do not suffer from it (?!?)... may be we shot ourselves in the foot with CVS... L. (*): I just saw that. For consistency (and try to preserve sanityi by avoiding code duplication) 'express' is very likely make use of 'computeExprSet' in the near future
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@warnes-gregory-r-43
Last seen 10.3 years ago
Also, which released version, 1.0 or 1.1? IE, how far back is did the bug go? -Greg > -----Original Message----- > From: Isaac Neuhaus [mailto:isaac.neuhaus@bms.com] > Sent: Tuesday, December 03, 2002 8:54 AM > To: Laurent Gautier > Cc: bioconductor@stat.math.ethz.ch > Subject: Re: [BioC] important bug fix in the package affy > > > Laurent: > > Can you elaborate a bit more? For example, is computeExprSet > an internal > function used by express or expresso? > > Isaac > > Gautier wrote: > > > To whom it makes concerned: > > > > The released version of the package problem suffered from a > rather annoying > > problem in the method 'computeExprSet'. As a result, the > expression values > > computed have very good chances to be rather incorrect > (whatever the method > > you used). Many thanks to Michael Morley for warning us > about strange results > > compared to MAS5.0 (the bug was found while digging that). > > I would strongly recommend to re-run expression value > computation with > > the version 1.1.1 of the package (should appear by > tomotrrow on the website) > > if you are currently working with expression data obtained with 1.1. > > > > Sorry for the inconvenience. > > > > Laurent > > > > _______________________________________________ > > Bioconductor mailing list > > Bioconductor@stat.math.ethz.ch > > http://www.stat.math.ethz.ch/mailman/listinfo/bioconductor > > _______________________________________________ > Bioconductor mailing list > Bioconductor@stat.math.ethz.ch > http://www.stat.math.ethz.ch/mailman/listinfo/bioconductor > LEGAL NOTICE Unless expressly stated otherwise, this message is confidential and may be privileged. It is intended for the addressee(s) only. Access to this E-mail by anyone else is unauthorized. If you are not an addressee, any disclosure or copying of the contents of this E-mail or any action taken (or not taken) in reliance on it is unauthorized and may be unlawful. If you are not an addressee, please inform the sender immediately.
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>>>>> "gregory" == Gregory R Warnes <warnes> writes: gregory> Also, which released version, 1.0 or 1.1? IE, how far back is did the bug gregory> go? 1.1. I don't know how far back, though. gregory> -Greg >> -----Original Message----- >> From: Isaac Neuhaus [mailto:isaac.neuhaus@bms.com] >> Sent: Tuesday, December 03, 2002 8:54 AM >> To: Laurent Gautier >> Cc: bioconductor@stat.math.ethz.ch >> Subject: Re: [BioC] important bug fix in the package affy >> >> >> Laurent: >> >> Can you elaborate a bit more? For example, is computeExprSet >> an internal >> function used by express or expresso? >> >> Isaac >> >> Gautier wrote: >> >> > To whom it makes concerned: >> > >> > The released version of the package problem suffered from a >> rather annoying >> > problem in the method 'computeExprSet'. As a result, the >> expression values >> > computed have very good chances to be rather incorrect >> (whatever the method >> > you used). Many thanks to Michael Morley for warning us >> about strange results >> > compared to MAS5.0 (the bug was found while digging that). >> > I would strongly recommend to re-run expression value >> computation with >> > the version 1.1.1 of the package (should appear by >> tomotrrow on the website) >> > if you are currently working with expression data obtained with 1.1. >> > >> > Sorry for the inconvenience. >> > >> > Laurent >> > >> > _______________________________________________ >> > Bioconductor mailing list >> > Bioconductor@stat.math.ethz.ch >> > http://www.stat.math.ethz.ch/mailman/listinfo/bioconductor >> >> _______________________________________________ >> Bioconductor mailing list >> Bioconductor@stat.math.ethz.ch >> http://www.stat.math.ethz.ch/mailman/listinfo/bioconductor >> gregory> LEGAL NOTICE gregory> Unless expressly stated otherwise, this message is confidential and may be privileged. It is intended for the addressee(s) only. Access to this E-mail by anyone else is unauthorized. If you are not an addressee, any disclosure or copying of the contents of this E-mail or any action taken (or not taken) in reliance on it is unauthorized and may be unlawful. If you are not an addressee, please inform the sender immediately. gregory> _______________________________________________ gregory> Bioconductor mailing list gregory> Bioconductor@stat.math.ethz.ch gregory> http://www.stat.math.ethz.ch/mailman/listinfo/bioconductor -- A.J. Rossini Rsrch. Asst. Prof. of Biostatistics U. of Washington Biostatistics rossini@u.washington.edu FHCRC/SCHARP/HIV Vaccine Trials Net rossini@scharp.org -------------- http://software.biostat.washington.edu/ ---------------- FHCRC: M: 206-667-7025 (fax=4812)|Voicemail is pretty sketchy/use Email UW: Th: 206-543-1044 (fax=3286)|Change last 4 digits of phone to FAX (my tuesday/wednesday/friday locations are completely unpredictable.)
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> >> Can you elaborate a bit more? For example, is computeExprSet > >> an internal > >> function used by express or expresso? Laurent can enlighten us later, but I am pretty sure computeExprSet is internal to expresso only. Ben
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On Tue, Dec 03, 2002 at 12:58:12PM -0800, A.J. Rossini wrote: > >>>>> "gregory" == Gregory R Warnes <warnes> writes: > > gregory> Also, which released version, 1.0 or 1.1? IE, how far back is did the bug > gregory> go? > > 1.1. > > I don't know how far back, though. Few weeks before the release in the devel version I suspect, since the release date for the version 1.1. The release date was Nov. 18th. The release version 1.0 was not subject to this bug. Truly sorry again about that. And I'd like to thank again people reporting bugs/oddities. L.
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