DiffBind individual sample concentrations for differentially bound sites
1
0
Entering edit mode
igor ▴ 50
@igor
Last seen 17 months ago
United States

I am using DiffBind to determine differentially bound sites. When you extract the sites with dba.report, the GRanges object contains the mean concentrations of the two groups. Is there a way to also get the concentrations of the individual samples?

 

diffbind granges • 1.2k views
ADD COMMENT
2
Entering edit mode
Rory Stark ★ 5.2k
@rory-stark-5741
Last seen 5 weeks ago
Cambridge, UK

Hello Igor-

If you set bCounts=TRUEin the call to dba.report() the report will include the read scores for each sample in the contrast. Also, remember that the group concentrations are log2()'ed.

Cheers-

Rory

ADD COMMENT
0
Entering edit mode

Thanks! I can't believe I missed that! I thought I went through the entire documentation multiple times.

ADD REPLY

Login before adding your answer.

Traffic: 616 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6