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Are there any plans to convert the RCytoscape package to use the REST interface in Cytoscape v3? There is an interesting proof of concept post from the Ideker lab now on Github here https://github.com/idekerlab/cy-rest-R
Well, if all goes well, it will be accepted into devel in the current release cycle. And then your package can depend on it. (Assuming your package is or is going to be a Bioconductor package; if not then you can do whatever you want). So I'd watch our twitter feed for the announcement that RCy3 has been added.