Number of Signatures in SomaticSignatures package
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Asma rabe ▴ 290
@asma-rabe-4697
Last seen 6.2 years ago
Japan

Hi,

I'm using SomaticSignatures package and i would like to find the best number of signatures that i should use. I could not find assessNumberSignatures function. 

I also could not find motifMatrix function but i could find mutationContextMatrix ​instead which is the same function as in the link below.

http://127.0.0.1:12716/library/SomaticSignatures/doc/SomaticSignatures-vignette.R

#============To assess Number of Signatures

n_sigs = 2:8
gof_nmf= assessNumberSignatures(Data, n_sigs, nReplicates = 5)
>Error: could not find function "assessNumberSignatures"

Has assessNumberSignatures been deprecated?  

#==========

Thank you in advance.

 

 

 

SomaticSignatures • 1.5k views
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Entering edit mode
Julian Gehring ★ 1.3k
@julian-gehring-5818
Last seen 5.0 years ago

It seems that you are have an old version of the package, while you are looking at the documentation of the current version (e.g. online via the Bioconductor web site). Please check with biocLite and/or the package website http://bioconductor.org/packages/release/bioc/html/SomaticSignatures.html that you have the latest version installed. At the time of writing, this is 2.4.5.

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Entering edit mode
Asma rabe ▴ 290
@asma-rabe-4697
Last seen 6.2 years ago
Japan

Thanks Julian. It works now

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