Entering edit mode
In DESeq2 paper:
edgeR [2,3] moderates the dispersion estimate for each gene toward a common estimate across all genes, or toward a local estimate from genes with similar expres- sion strength, using a weighted conditional likelihood.
However, as far as I understood the dispersion estimate in DESeq2 is also squeezed toward a common estimate but it controls for the amount of shrinkage.
Is it correct?