I have the entrez IDs of 100 proteins and I have put them in a list and been trying to use R's mgeneSim function from the GOSemSim package, but I am getting the following error:
> mgeneSim(protein_id_list, organism="human")
<0 x 0 matrix>
There were 50 or more warnings (use warnings() to see the first 50)
> warnings()
Warning messages:
1: In is.na(go) : is.na() applied to non-(list or vector) of type 'NULL'
2: In is.na(go) : is.na() applied to non-(list or vector) of type 'NULL'
3: In is.na(go) : is.na() applied to non-(list or vector) of type 'NULL'
The contents of the list are:
> protein_id_list
[1] "O14757" "P49760" "P07333" "P48729" "O43293" "Q13627" "P11362" "P17948" "P36888" "P06241" "P49840" "P49841"
[13] "P08069" "O60674" "P52333" ...
Even the following code fails:
> mgeneSim(c("Q9Y243", "P06213"))
Warning messages:
1: In is.na(go) : is.na() applied to non-(list or vector) of type 'NULL'
2: In is.na(go) : is.na() applied to non-(list or vector) of type 'NULL'