ChAMP ComBat step error: Error in if (min(beta.c) == 0) { : missing value where TRUE/FALSE needed
0
0
Entering edit mode
@daniel-e-weeks-10677
Last seen 12 months ago
Pittsburgh, Pennsylvania, United States…

When trying to run ChAMP version 1.8.2 on a data set of 91 samples using the default champ.process command, it got through the SVD step, but then died at the ComBat step:

Preparing files for ComBat
Error in if (min(beta.c) == 0) { : missing value where TRUE/FALSE needed
Calls: champ.process -> champ.runCombat
In addition: Warning messages:
1: In min(beta2.v[selMR.idx]) :
  no non-missing arguments to min; returning Inf
2: In min(nbeta2.v[selMR.idx]) :
  no non-missing arguments to min; returning Inf
3: In min(beta2.v[selMR.idx]) :
  no non-missing arguments to min; returning Inf
4: In min(nbeta2.v[selMR.idx]) :
  no non-missing arguments to min; returning Inf
5: In min(beta2.v[selMR.idx]) :
  no non-missing arguments to min; returning Inf
6: In min(nbeta2.v[selMR.idx]) :
  no non-missing arguments to min; returning Inf
Execution halted

 

In champ.norm, I see code like this:

if (min(beta.p, na.rm = TRUE) == 0) {

but in champ.runCombat, I see this (which lacks the na.rm option):

if (min(beta.c) == 0) {

I am not sure how to debug this.  

Thank you.

 

 

 

ChAMP methylation illumina450k • 1.5k views
ADD COMMENT

Login before adding your answer.

Traffic: 558 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6