Hi there,
I'm interested in converting a MethylSet back to an RGChannelSet object for purposes of preprocessing (I am using unprocessed data obtained from GEO), but I'm unsure of how to do this.
My understanding is that preprocessRaw() uses manifest info to associate idat channels with the correct array probes. I'm not aware of a function that does this in reverse. I'm thinking it should be possible to do this manually with a few for loops, but the rownames for getGreen() and getRed() matrices from the RGChannelSet are numeric identifiers. I am unsure of how to go about identifying which channels go to which array probe.
I am running minfi 1.18.6 and Bioconductor 3.3.
Thanks!
Sean
Kasper,
Thanks for your reply. I was hoping that, despite the missing data, I would be able to fill in the limited data I have in order to perform normalizations that don't require the other kinds of probes and intensities.
Sean