I am trying to use "getGSEDataTables" from GSEquery package, but it gives the following error:

> dfl = getGSEDataTables("GSE3494")
error : Unknown IO error
I/O warning : failed to load external entity "http://www.ncbi.nlm.nih.gov/projects/geo/query/acc.cgi?targ=self&form=xml&view=full&acc=GSE3494"
Error in UseMethod("xmlRoot") : 
  no applicable method for 'xmlRoot' applied to an object of class "NULL"

My session info:

> sessionInfo()
R version 3.2.3 (2015-12-10)
Platform: x86_64-apple-darwin14.5.0 (64-bit)
Running under: OS X 10.11.3 (El Capitan)

locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

attached base packages:
[1] stats4    parallel  stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] GEOquery_2.36.0              devtools_1.9.1               hgu133ahsentrezg.db_20.0.0   org.Hs.eg.db_3.2.3          
 [5] pd.hgu133a.hs.entrezg_0.0.1  oligo_1.34.2                 oligoClasses_1.32.0          RSQLite_1.0.0               
 [9] DBI_0.3.1                    Biostrings_2.38.4            XVector_0.10.0               hgu133ahsentrezgprobe_20.0.0
[13] hgu133ahsentrezgcdf_20.0.0   AnnotationDbi_1.32.3         IRanges_2.4.8                S4Vectors_0.8.11            
[17] gcrma_2.42.0                 affy_1.48.0                  Biobase_2.30.0               BiocGenerics_0.16.1         
[21] BiocInstaller_1.20.1        

loaded via a namespace (and not attached):
 [1] GenomeInfoDb_1.6.3         bitops_1.0-6               iterators_1.0.8            tools_3.2.3               
 [5] zlibbioc_1.16.0            digest_0.6.8               bit_1.1-12                 memoise_0.2.1             
 [9] preprocessCore_1.32.0      ff_2.2-13                  foreach_1.4.3              curl_0.9.4                
[13] httr_1.0.0                 stringr_1.0.0              affxparser_1.42.0          R6_2.1.1                  
[17] XML_3.98-1.3               magrittr_1.5               codetools_0.2-14           splines_3.2.3             
[21] GenomicRanges_1.22.4       SummarizedExperiment_1.0.2 stringi_1.0-1              RCurl_1.95-4.7            
[25] affyio_1.40.0           

Hello,

I get the same error, and wondered if you have any suggestions to fix it.

Thanks

Sharvari

Sorry I missed this question the first time.  The solution is to upgrade to GEOquery 2.40 or higher due to a change at NCBI from "http" to "https".