Hi:

Before diving into analysis of (public) RNAseq data, I discovered that the data are stored in two BigWig files per sample (i.e. carrying a 'neg' identifier, the other a 'pos' identifier). Unfortunately I am not very familiar with handling BigWigs, so my question is: should I somehow combine these two, and importantly, how would I be able to achieve such?

Many thanks in advance for your advice/pointers,

Bas