DMRcate
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dgrayson • 0
@3d63af48
Last seen 2.0 years ago
United States

How is the minFDR value calculated for each cluster of CpG probes that are identified when running DMRcate on EPIC BeadChip data? I have a large number of differentially methylated positions (DMPs) which are not significant based on Q value calculations when looking at the DMP-level data. However, when looking at the DMR results, DMR-level data, there are maybe 1500 groups (or clusters) of proximal probes that have minFDR values less than 0.05. Does anyone know how this calculation is made? Thanks very much. I apologize if this is posted in the wrong place. Dennis ```

DMRcatedata • 520 views
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