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Code should be placed in three backticks as shown below

library(gplots)

x <- genes
y <- data.matrix(genes)
y
heatmap.2(genes)


?heatmap.2
heatmap.2(y, main="Sample", trace= "none", margins= c(23,24))


yb <- colorRampPalette(c("yellow", "white", "blue"))
heatmap.2(y, color=yb, main="Sample", trace= "none", margins= c(23,24), cexRow = 0.5, Rowv = FALSE, Colv = FALSE, key)

# include your problematic code here with any corresponding output 
# please also include the results of running the following in an R session 

sessionInfo( )

Error in .External.graphics(C_layout, num.rows, num.cols, mat, as.integer(num.figures), : invalid graphics state In addition: Warning messages: 1: In heatmap.2(y, color = yb, main = "Sample", trace = "none", margins = c(23, : Discrepancy: Rowv is FALSE, while dendrogram is both'. Omitting row dendogram. 2: In heatmap.2(y, color = yb, main = "Sample", trace = "none", margins = c(23, : Discrepancy: Colv is FALSE, while dendrogram iscolumn'. Omitting column dendogram.

heatmap.2(y, main="Sample", trace= "none", margins= c(23,24))

The heatmap.2 function is part of the gplots package, which is not part of Bioconductor. Since this is a support site for Bioconductor packages, the question is off-topic. You could try r-help@r-project.org or maybe stackoverflow.com, or simply try restarting R.