Does it make sense to have so many statistically significant gene differentially expressed after DESeq2 paired sample analysis?
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@06de5a1f
Last seen 13 hours ago
Germany

Does it make sense to have so many statistically significant gene differentially expressed after DESeq2 paired sample analysis? for example 7000 statistically significant genes out of 100000?

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@mikelove
Last seen 1 day ago
United States

Yes, this has been asked before on the support site, with paired analysis, you can have higher power.

Just look at plotCounts for representative genes.