Good morning, I am trying to apply HicDCPlus to a set of samples following the vignette code. However, I often get the following error when processing bigger chromosomes:

Chromosome chr1 complete.
Error in gi_list_write(gi_list, fname = output_path) :
  R_Reprotect: only 4 protected items, can't reprotect index -1

I tried to substitute the tmp folder with a local stable folder, but that did not solve the issue completely. Notice that I have installed the package from bitbucket as I am using R 4.0.2.

From my understanding, this has to do with the allocation of space for temporary files, but I haven't been able to understand this further. Any clue of what's going on?

Thank you

Here is my session info

sessionInfo()
R version 4.0.2 (2020-06-22)
Platform: x86_64-conda_cos6-linux-gnu (64-bit)
Running under: CentOS Linux 7 (Core)

Matrix products: default
BLAS/LAPACK: /mnt/pd2/gianmarco/miniconda3/lib/libopenblasp-r0.3.12.so

locale:
 [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C
 [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8
 [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8
 [7] LC_PAPER=en_US.UTF-8       LC_NAME=C
 [9] LC_ADDRESS=C               LC_TELEPHONE=C
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C

attached base packages:
[1] stats4    parallel  stats     graphics  grDevices utils     datasets
[8] methods   base

other attached packages:
 [1] BSgenome.Hsapiens.UCSC.hg19_1.4.3 BSgenome_1.58.0
 [3] rtracklayer_1.50.0                Biostrings_2.58.0
 [5] XVector_0.30.0                    GenomicRanges_1.42.0
 [7] GenomeInfoDb_1.26.7               IRanges_2.24.1
 [9] S4Vectors_0.28.1                  BiocGenerics_0.36.1
[11] HiCDCPlus_0.99.14                 data.table_1.14.2
[13] forcats_0.5.1                     stringr_1.4.0
[15] dplyr_1.0.7                       purrr_0.3.4
[17] readr_2.1.1                       tidyr_1.1.4
[19] tibble_3.1.6                      ggplot2_3.3.5
[21] tidyverse_1.3.1

loaded via a namespace (and not attached):
  [1] colorspace_2.0-2            ellipsis_0.3.2
  [3] htmlTable_2.3.0             biovizBase_1.38.0
  [5] base64enc_0.1-3             fs_1.5.2
  [7] dichromat_2.0-0             rstudioapi_0.13
  [9] bit64_4.0.5                 AnnotationDbi_1.52.0
 [11] fansi_0.5.0                 lubridate_1.8.0
 [13] xml2_1.3.3                  splines_4.0.2
 [15] R.methodsS3_1.8.1           cachem_1.0.6
 [17] knitr_1.36                  Formula_1.2-4
 [19] jsonlite_1.7.2              Rsamtools_2.6.0
 [21] broom_0.7.10                cluster_2.1.2
 [23] dbplyr_2.1.1                png_0.1-7
 [25] R.oo_1.24.0                 compiler_4.0.2
 [27] httr_1.4.2                  backports_1.4.0
 [29] lazyeval_0.2.2              assertthat_0.2.1
 [31] Matrix_1.4-0                fastmap_1.1.0
 [33] cli_3.1.0                   htmltools_0.5.2
 [35] prettyunits_1.1.1           tools_4.0.2
 [37] igraph_1.2.9                gtable_0.3.0
 [39] glue_1.5.1                  GenomeInfoDbData_1.2.4
 [41] rappdirs_0.3.3              Rcpp_1.0.7
 [43] Biobase_2.50.0              cellranger_1.1.0
 [45] vctrs_0.3.8                 xfun_0.28
 [47] librarian_1.8.1             rvest_1.0.2
 [49] lifecycle_1.0.1             ensembldb_2.14.1
 [51] XML_3.99-0.8                InteractionSet_1.18.1
 [53] MASS_7.3-54                 zlibbioc_1.36.0
 [55] scales_1.1.1                VariantAnnotation_1.36.0
 [57] ProtGenerics_1.22.0         GenomicInteractions_1.24.0
 [59] hms_1.1.1                   MatrixGenerics_1.2.1
 [61] SummarizedExperiment_1.20.0 AnnotationFilter_1.14.0
 [63] RColorBrewer_1.1-2          curl_4.3.2
 [65] gridExtra_2.3               memoise_2.0.1
 [67] rpart_4.1-15                biomaRt_2.46.3
 [69] latticeExtra_0.6-29         stringi_1.7.6
 [71] RSQLite_2.2.9               checkmate_2.0.0
 [73] GenomicFeatures_1.42.3      BiocParallel_1.24.1
 [75] rlang_0.4.12                pkgconfig_2.0.3
 [77] matrixStats_0.61.0          bitops_1.0-7
 [79] lattice_0.20-45             htmlwidgets_1.5.4
 [81] GenomicAlignments_1.26.0    bit_4.0.4
 [83] tidyselect_1.1.1            magrittr_2.0.1
 [85] R6_2.5.1                    generics_0.1.1
 [87] Hmisc_4.6-0                 DelayedArray_0.16.3
 [89] DBI_1.1.1                   foreign_0.8-81
 [91] pillar_1.6.4                haven_2.4.3
 [93] withr_2.4.3                 nnet_7.3-16
 [95] survival_3.2-13             RCurl_1.98-1.5
 [97] modelr_0.1.8                crayon_1.4.2
 [99] utf8_1.2.2                  BiocFileCache_1.14.0
[101] tzdb_0.2.0                  jpeg_0.1-9
[103] progress_1.2.2              grid_4.0.2
[105] readxl_1.3.1                blob_1.2.2
[107] reprex_2.0.1                digest_0.6.29
[109] R.utils_2.11.0              openssl_1.4.5
[111] munsell_0.5.0               Gviz_1.34.1
[113] askpass_1.1