affy package and SNP arrays
0
0
Entering edit mode
@vincent-j-carey-jr-4
Last seen 8 weeks ago
United States

Howdy. There is now a github repo for the affy package where a question about processing SNP6 chips with rma was raised. I am posting this issue here to indicate to the world that IMHO crlmm is the package to use for preprocessing affy SNP chips -- but I have not kept close watch on this topic and others may have better information. I can confirm that

BiocManager::install("crlmm")
BiocManager::install('genomewidesnp6Crlmm')
BiocManager::install("hapmapsnp6")
library(crlmm)
example(snprma2)

works with

> sessionInfo()
R version 4.3.0 (2023-04-21)
Platform: x86_64-pc-linux-gnu (64-bit)
Running under: Ubuntu 22.04.2 LTS

Matrix products: default
BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.10.0 
LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.10.0

locale:
 [1] LC_CTYPE=C.UTF-8       LC_NUMERIC=C           LC_TIME=C.UTF-8       
 [4] LC_COLLATE=C.UTF-8     LC_MONETARY=C.UTF-8    LC_MESSAGES=C.UTF-8   
 [7] LC_PAPER=C.UTF-8       LC_NAME=C              LC_ADDRESS=C          
[10] LC_TELEPHONE=C         LC_MEASUREMENT=C.UTF-8 LC_IDENTIFICATION=C   

time zone: Etc/UTC
tzcode source: system (glibc)

attached base packages:
[1] stats     graphics  grDevices datasets  utils     methods   base     

other attached packages:
[1] hapmapsnp6_1.42.0         genomewidesnp6Crlmm_1.0.7
[3] crlmm_1.58.0              preprocessCore_1.62.1    
[5] oligoClasses_1.62.0       affy_1.78.0              
[7] Biobase_2.60.0            BiocGenerics_0.46.0      

loaded via a namespace (and not attached):
 [1] Matrix_1.5-4.1              bit_4.0.5                  
 [3] limma_3.56.2                compiler_4.3.0             
 [5] BiocManager_1.30.21         crayon_1.5.2               
 [7] Rcpp_1.0.10                 SummarizedExperiment_1.30.2
 [9] ellipse_0.4.5               bspm_0.5.2                 
[11] GenomicRanges_1.52.0        bitops_1.0-7               
[13] Biostrings_2.68.1           parallel_4.3.0             
[15] VGAM_1.1-8                  splines_4.3.0              
[17] IRanges_2.34.0              lattice_0.21-8             
[19] XVector_0.40.0              S4Arrays_1.0.1             
[21] RcppEigen_0.3.3.9.3         GenomeInfoDb_1.36.0        
[23] ff_4.0.9                    iterators_1.0.14           
[25] DelayedArray_0.26.3         MatrixGenerics_1.12.0      
[27] openssl_2.0.6               GenomeInfoDbData_1.2.7     
[29] DBI_1.1.3                   affyio_1.70.0              
[31] illuminaio_0.42.0           base64_2.0.1               
[33] zlibbioc_1.46.0             foreach_1.5.2              
[35] grid_4.3.0                  mvtnorm_1.2-2              
[37] askpass_1.1                 beanplot_1.3.1             
[39] S4Vectors_0.38.1            codetools_0.2-19           
[41] stats4_4.3.0                RCurl_1.98-1.12            
[43] matrixStats_1.0.0           tools_4.3.0
crlmm hapmapsnp6 genomewidesnp6Crlmm affy • 854 views
ADD COMMENT
0
Entering edit mode

aroma.affymetrix is available on CRAN and can be used for SNP6; however, I think that it ultimately uses quite a few Bioconductor packages behind the scenes.

ADD REPLY

Login before adding your answer.

Traffic: 412 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6