Cluster profiler emap plot - what are the annotations?
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fluentin44 • 0
@45f45212
Last seen 7 months ago
United Kingdom

Hi,

Using clusterprofiler an generated an emap plot from my enrichment data - would anyone be able to tell me where the grouping terms (bottom right) come from / how they are made? They look potentially like they are just picking common words?

emap plot

Thanks, Matt

clusterProfiler emapplot • 840 views
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Guido Hooiveld ★ 3.9k
@guido-hooiveld-2020
Last seen 12 hours ago
Wageningen University, Wageningen, the …

Yes, these (the groups) are indeed 'high frequency words' present in the terms/descriptions of the gene set; identified analogous when creating a word cloud.

This is indeed not clearly stated at the help page for the function emapplot, but it becomes obvious if you check the source code at line 523:

https://github.com/YuLab-SMU/enrichplot/blob/ce94b308d0ce5e835117bacd8858aadf2b2de9bc/R/emapplot_utilities.R#L523C44-L524

... you will notice that there the internal function get_wordcloud is called, which can be found here: https://github.com/YuLab-SMU/enrichplot/blob/ce94b308d0ce5e835117bacd8858aadf2b2de9bc/R/wordcloud.R#L26

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Absolutely brilliant, thanks for a definitive answer!

Thanks, Matt

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