Is there a simple way to create a TidySummarizedExperiment object from an existing kind of SummarizedExperiment? I am pulling data from recount3 and want to manipulate it using tidyr-like functions.

I don't believe there is such a thing as a TidySummarizedExperiment. The tidySummarizedExperiment appears to simply allow one to interact with the SummarizedExperiment class as if it were a tibble.