Comrades! Long time no repartee ...
I thought it would be nigh time to upgrade my bioc install to the latest and greatest (bioc3.22), so I gave it a whirl.
I've recently been trying to do some magic with MeSH terms, and wanted to download the latest mouse (AH121915) and human (AH121907) MeSHDb files (v010) from AnnotationHub, however it's throwing an error while trying to download the files .. something about not being able to resolve the host (bioconductorhubs.blob.core.windows.net) that it looks like it's trying to pull these files from.
Witness:
library(AnnotationHub)
ah <- AnnotationHub()
# Note that these are the files I'm after
ah[c("AH121915", "AH121907")]]
# ...
# title
# AH121915 | MeSHDb for Mus musculus (Mouse, v010)
# AH121907 | MeSHDb for Homo sapiens (Human, v010)
Trying to download either of these files, like so:
mesh.hs <- ah[["AH121915"]]
Results in the following error:
downloading 1 resources
retrieving 1 resource
Error loading resource.
attempting to re-download
downloading 1 resources
retrieving 1 resource
Warning messages:
1: download failed
web resource path: 'https://annotationhub.bioconductor.org/fetch/128661'
local file path: '/Users/steve/Library/Caches/org.R-project.R/R/AnnotationHub/7b382f3dffdf_128661'
reason: Failed to perform HTTP request.
Caused by error in `curl::curl_fetch_disk()`:
! Could not resolve hostname [bioconductorhubs.blob.core.windows.net]:
Could not resolve host: bioconductorhubs.blob.core.windows.net
2: bfcadd() failed; resource removed
rid: BFC22
fpath: 'https://annotationhub.bioconductor.org/fetch/128661'
reason: download failed
3: download failed
hub path: 'https://annotationhub.bioconductor.org/fetch/128661'
cache resource: 'AH121915 : 128661'
reason: bfcadd() failed; see warnings()
4: download failed
web resource path: 'https://annotationhub.bioconductor.org/fetch/128661'
local file path: '/Users/steve/Library/Caches/org.R-project.R/R/AnnotationHub/7b38f69a1b4_128661'
reason: Failed to perform HTTP request.
Caused by error in `curl::curl_fetch_disk()`:
! Could not resolve hostname [bioconductorhubs.blob.core.windows.net]:
Could not resolve host: bioconductorhubs.blob.core.windows.net
5: bfcadd() failed; resource removed
rid: BFC23
fpath: 'https://annotationhub.bioconductor.org/fetch/128661'
reason: download failed
6: download failed
hub path: 'https://annotationhub.bioconductor.org/fetch/128661'
cache resource: 'AH121915 : 128661'
reason: bfcadd() failed; see warnings()
Error:
! failed to load resource
name: AH121915
title: MeSHDb for Mus musculus (Mouse, v010)
reason: 1 resources failed to download
Am I doing something wrong, or?
Also, here is my sessionInfo, thanks!
R version 4.5.2 (2025-10-31)
Platform: aarch64-apple-darwin20
Running under: macOS Sequoia 15.7.1
Matrix products: default
BLAS: /System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libBLAS.dylib
LAPACK: /Library/Frameworks/R.framework/Versions/4.5-arm64/Resources/lib/libRlapack.dylib; LAPACK version 3.12.1
locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
time zone: America/Los_Angeles
tzcode source: internal
attached base packages:
[1] stats graphics grDevices utils datasets methods base
other attached packages:
[1] AnnotationHub_4.0.0 BiocFileCache_3.0.0 dbplyr_2.5.1 BiocGenerics_0.56.0 generics_0.1.4
loaded via a namespace (and not attached):
[1] bit_4.6.0 crayon_1.5.3 dplyr_1.1.4 compiler_4.5.2 BiocManager_1.30.26 filelock_1.0.3 tidyselect_1.2.1 Biobase_2.70.0
[9] blob_1.2.4 Biostrings_2.78.0 Seqinfo_1.0.0 IRanges_2.44.0 png_0.1-8 yaml_2.3.10 fastmap_1.2.0 XVector_0.50.0
[17] R6_2.6.1 curl_7.0.0 httr2_1.2.1 tibble_3.3.0 AnnotationDbi_1.72.0 DBI_1.2.3 pillar_1.11.1 rlang_1.1.6
[25] KEGGREST_1.50.0 cachem_1.1.0 bit64_4.6.0-1 RSQLite_2.4.3 memoise_2.0.1 cli_3.6.5 withr_3.0.2 magrittr_2.0.4
[33] rappdirs_0.3.3 lifecycle_1.0.4 S4Vectors_0.48.0 vctrs_0.6.5 glue_1.8.0 stats4_4.5.2 purrr_1.2.0 BiocVersion_3.22.0
[41] httr_1.4.7 tools_4.5.2 pkgconfig_2.0.3

That fixed it, thanks Lori!