Job:University of Cambridge- Research Associate (Bioinformatician) (Fixed Term)
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kraiczy ▴ 10
Last seen 7.4 years ago

Research Associate (Bioinformatician) (Fixed Term)

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Applications are invited for the post of a Post-doctoral Bioinformatician to work on a collaborative translational research project between the groups of Dr Matthias Zilbauer (Department of Paediatrics at the University of Cambridge, UK), Dr. Paul Lyons (Department of Medicine, University of Cambridge, UK) and Dr. Oliver Stegle (European Bioinformatics Institute - EBI, UK).

The overall aim of this project is to apply genome wide/whole genome profiling approaches to a large, prospectively recruited human tissue sample collection in order to investigate disease pathogenesis as well as develop clinical biomarkers for patients suffering from Inflammatory Bowel Diseases (IBD). A second focus lies on elucidating the role of epigenetic mechanisms in regulating cellular function in the human intestinal tract during physiological development and disease using human organoid culture models.

The selected candidate will have the opportunity to work with a group of international leaders in the field of translational research (e.g. Kraiczy et al. Mucosal Immunology 2016, Cannavò E et al Nature 2017, Baud A et al, PLoS genetics 2017, McKinney EF et al Nature 2015) and apply cutting edge computational biology approaches to unique datasets derived from disease relevant human tissue/cell samples.

Both the University of Cambridge and European Bioinformatics Institute EBI provide unique opportunities for training and personal development.

Applications are invited from researchers with a PhD, and a proven track record in computational biology (evidence of one or more high impact publications in a relevant research field). Programming ability and proven skills in advanced statistics/probability and machine learning are essential.

Previous experience in RNA and DNA sequencing, gene regulation and expression analysis, and/or modeling of data from genetic fate mapping studies, is desired. Applicants should have excellent interpersonal and communication skills, and the ability to work as part of a team as well as independently when required. We particularly welcome applicants with a background in mathematics, physics, or computer science who wish to develop their knowledge of biology and translational biomedical research.

PhD students who are close to completing their thesis will also be considered. Knowledge of spoken and written English is required, experience in manuscript preparation and or grant writing are desirable.

Informal enquiries can be addressed to Dr Matthias Zilbauer (

Websites: Matthias Zilbauer

Oliver Stegle

Paul Lyons

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy, please click on the link below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form. Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Closing date for applications is 26th March 2017 with interviews likely to take place April 2017.Please quote reference RP11488 on your application and in any correspondence about this vacancy.

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