Question: VIPER (Protein Activity Inference) gene expression signature format
gravatar for user31888
2.2 years ago by
United States
user3188830 wrote:

Can we run VIPER (described here) with gene expression signatures generated from RNASeq-based differential expression experiments (e.g. DESeq, EdgeR, ...) instead of microarray data?

VIPER manual mentions "It can also take two matrixes as arguments, the first one containing the ‘test’ samples and the second the ‘reference’ samples"

If yes, which metrics to use (normalised read count, fold change, p-value...)?

How to pre-process this type of data?

Thanks !


viper aracne.networks • 482 views
ADD COMMENTlink modified 2.2 years ago • written 2.2 years ago by user3188830
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