Hello,
I used PSCBS and the aroma package to obtain copy number from tumor normal pairs. The code runs fine and I end up with a text file with copy number of segments. I'm however unable to figure out the meaning of some of the columns in the result file(tcnNbrOfLoci, tcnNbrOfSNPs, tcnNbrOfHets, dhNbrOfLoci). I'm also unable to find documentation that clarifies what these columns are. I'll be grateful for any explanation on what these columns stand for or a pointer to the appropriate documentation.
I have also attached a snippet of the result file below.
Thanking You,
Vakul
chromosome tcnId dhId start end tcnNbrOfLoci tcnMean tcnNbrOfSNPs tcnNbrOfHets dhNbrOfLoci dhMean c1Mean c2Mean rohCall abCall lohCall ntcnCall
1 1 1 61736 356493.5 29 2.0454 0 0 0 NA NA NA NA NA NA TRUE
1 2 1 356493.5 41027889.5 22688 1.5614 3209 3209 3209 0.0956 0.70606508 0.85533492 FALSE FALSE FALSE TRUE
1 3 1 41027889.5 41666838.5 354 1.7366 45 45 45 0.111 0.7719187 0.9646813 FALSE FALSE FALSE TRUE