log transform or not the dependent variable/ covariates
0
0
Entering edit mode
@annacotannacot-20795
Last seen 19 months ago
United States

Would you please advice me if the dependent variables in edgeR and limma should be used as a raw measurements or should they be log transformed if they are skewed?

limma edgeR • 916 views
ADD COMMENT
1
Entering edit mode

Your question is lacking in details. Can you elaborate on what data you have, what you aim to do with it, and which [if any] errors / issues / problems that you have encountered?

ADD REPLY
1
Entering edit mode

Your question says "dependent variable" but I am guessing that you mean independent variables of a numerical type, i.e., covariates.

There is no blanket rule about whether covariates should be transformed or not. Anything that make sense in the linear model is ok. It depends on the context. A covariate does not have to normally distributed.

ADD REPLY

Login before adding your answer.

Traffic: 583 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6