User: Sebastian Hesse

Reputation:
10
Status:
New User
Location:
Germany / Munich / Dr.von Hauner Children's Hospital
Scholar ID:
Google Scholar Page
Last seen:
2 weeks ago
Joined:
3 weeks, 4 days ago
Email:
h**************@googlemail.com

Posts by Sebastian Hesse

<prev • 6 results • page 1 of 1 • next >
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Comment: C: Define batch effect variables before removing them or getting rid of hidden surr
... I found a package plotting exactly what I wanted called PVCA. Now the problem arises, that I have quite a lot of candidates for batch effects and I will beed to decide which ones to correct for. I opened a new question for that here: https://support.bioconductor.org/p/115278/ Any comments here or a ...
written 21 days ago by Sebastian Hesse10
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Interpretation of PVCA result and what to correct for
... Thanks to PVCA I finally found a tool to check the effect of all my suspected confounders I annotated in my proteome project. But now my problem is that I don't really know what to correct for and what to better leave. https://ibb.co/bUCX4f   First, should I now remove all major effects (eg da ...
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Comment: C: ComBat with multiple batches
... Hi ben.run974, did you find a solution yet if this is the correct way? Thanks! Sebastian ...
written 21 days ago by Sebastian Hesse10
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Comment: C: Error in solve.default(t(mod) %*% mod) : Lapack routine dgesv: system is exactl
... Hi Aina, did you find a solution yet? I get the very same error.... Thanks! Sebastian   ...
written 21 days ago by Sebastian Hesse10
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Define batch effect variables before removing them or getting rid of hidden surrogate variables
... Dear community, much has been written and asked on this topic but I'm still a bit confused and would appreciate it very much to get a defined guideline on how to handle batch effects in omics datasets (in my case proteomics but its probably applicable to any). So I do have two data frames, one con ...
proteomics sva batch effect correction written 25 days ago by Sebastian Hesse10
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Comment: C: sva: how to incorporate adjusting variables
... Dear Olivia, dear Jeff, though this thread is a bit dated I am facing the same problem here and maybe Olivia has found and answer since a long time (I certainly hope so for you :) I am wondering how you determined which factors do have an influence on your data in the first place? How can we deter ...
written 25 days ago by Sebastian Hesse10

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