Question: topGO (Version: 2.30.1) - weight01 algorithm
1
gravatar for digrigor
15 months ago by
digrigor10
digrigor10 wrote:

Hello,

I am using topGO to conduct a enrichment analysis for gene ontology for differentialy expressed genes determined from my RNA-Seq data.

Currently, I am trying to compare between "elim", "weight" and "weight01" algorithms. 

"elim" and "weight" algorithms are really well explained in the cited article: https://academic.oup.com/bioinformatics/article/22/13/1600/193669 . However, for the "weight01" algorithm there is only a short explanation in the provided vignette saying: "weight01 is a mixture between the elim and the weight algorithms and it will be referred as weight01". 

Could someone help me understand how "weight01" values are calculated? 

Is there any article I am missing regarding to the calculation of the weight01 values?

Thank you,

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