Question: Is C adjusted for purity?
0
gravatar for twtoal
10 months ago by
twtoal0
twtoal0 wrote:

Several PureCN output files have "C" columns containing estimated copy number.  Is the data in these columns adjusted for purity?  That is, do they reflect the copy number of the tumor tissue and not the normal tissue that is mixed in with it?  If not, am I correct to think that the adjustment would be:

Adjusted_C = (Unadjusted_C - 2*(1-purity)) / purity

 

purecn adjusted c • 182 views
ADD COMMENTlink modified 10 months ago by markus.riester110 • written 10 months ago by twtoal0
Answer: Is C adjusted for purity?
0
gravatar for markus.riester
10 months ago by
markus.riester110 wrote:

Yes, these are already  adjusted. No need for manual calculations. 

ADD COMMENTlink written 10 months ago by markus.riester110
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