Question: Is C adjusted for purity?
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13 months ago by
twtoal0
twtoal0 wrote:

Several PureCN output files have "C" columns containing estimated copy number.  Is the data in these columns adjusted for purity?  That is, do they reflect the copy number of the tumor tissue and not the normal tissue that is mixed in with it?  If not, am I correct to think that the adjustment would be:

Adjusted_C = (Unadjusted_C - 2*(1-purity)) / purity

purecn adjusted c • 223 views
modified 13 months ago by markus.riester110 • written 13 months ago by twtoal0
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13 months ago by
markus.riester110 wrote: