May I clarify a part of the DESeq2 package? Is it true that DESeq2 counts for linear (only) transcripts and excludes any possibility in circular RNA (circRNA)? In which, an increase/decrease in circRNA has no effect on the number of counts produced in the results/output? Or does DESeq2 not able to distinguish the two, will assume circRNA as linear fragments, and include it into the counts?
Question: Is circular RNA read out as linear fragments during Rsubread-DESeq2
4 weeks ago by
csijst • 0
Singapore/National University of Singapore
csijst • 0 wrote:
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