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Question: Interactions and contrasts for DE analysis in ballgown
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gravatar for khill33
12 weeks ago by
khill330
khill330 wrote:

Hi!

 

Is it possible to test for differential expression among interactions and contrasts in Ballgown? I have a treatment group (drug/control) and sex (m/f). I would like to know the effect of each interaction drug*male, drug*female, control*male, control*female. 

 

Thanks!

ADD COMMENTlink modified 12 weeks ago by James W. MacDonald47k • written 12 weeks ago by khill330
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gravatar for James W. MacDonald
12 weeks ago by
United States
James W. MacDonald47k wrote:

Have you read the ballgown vignette? You can pass in two design matrices, one in which you have dropped the coefficients you want to test, so it should be straightforward to test for an interaction.

ADD COMMENTlink written 12 weeks ago by James W. MacDonald47k
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