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Question: Horizontal integration of multi omic data, with continuous dependent variable
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gravatar for dberel
4 months ago by
dberel20
dberel20 wrote:

Horizontal integration of multi omic data is combining and integrating independent studies measured on the same P predictors (e.g. genes).

mixOmics/MINT suggest such method with a binary dependent variable, though I look for a continuous one (regression).

Any suggestions?

Dror.

ADD COMMENTlink modified 4 months ago by Levi Waldron790 • written 4 months ago by dberel20
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gravatar for Levi Waldron
4 months ago by
Levi Waldron790
CUNY Graduate School of Public Health and Health Policy, New York, NY
Levi Waldron790 wrote:

I'm not totally clear on what your goal is, but it sounds possibly you want to do regression on a continuous dependent variable. If that's the case, you might check out:

MultiAssayExperiment's intersectColumns(), intersectRows(), assays(), wideFormat(), longFormat(), and subsetting methods should allow you to get to the formats and data required by any of these packages pretty efficiently.

ADD COMMENTlink written 4 months ago by Levi Waldron790
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