statistics behind the enrichPeakOverlap function in ChIPseeker package
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majingqun • 0
@majingqun-16620
Last seen 5.8 years ago

when performing the Shuffle within enrichPeakOverlap function, which peaks are being shuffled? the query or the target peak? How the p value is a computed? The source code would be helpful here.

When I interchange the query and target peaks, the output are totally different, could change from significant to non-significant. The same two peaks, just depend on which is feed into the query versus the target, the result changed completely. I would appreciate your insight on this issue. since this issue makes interoperate the result(p.adjust) unreliable. 

bioconductor • 455 views
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