Question: Error in saving diffmeth data
gravatar for kjfilipski
15 months ago by
kjfilipski0 wrote:

Dear bioconductor team,


I am trying to use RnBeads to analyse DNA methylation data. I am especially interested in differential methylation. Unfortunately I get the following error (originally in german): 


error in save.rnb.diffmeth(diffmeth, diffmeth.path) : try to call a slot "disk.dump" from an object of the simple class ("NULL") without slots


Could you please help me?


Best regards,


Katharina Filipski


error • 275 views
ADD COMMENTlink written 15 months ago by kjfilipski0

Have you found the issue / solved the problem? We are running into the same problem.

ADD REPLYlink written 5 weeks ago by P Darakjian40

I have managed to complete the analysis once I inspected the sample annotation file for issues with tabs vs spaces. I also added the column "Sample_Name" in addition to "Sample_ID" (Sample_IDs are the names of the bed files for each sample). You also must inspect the rnb.options to make sure the identifiers.column is set to the correct column name in the sample annotation file (same thing for the covariate.adjustment.columns option).

ADD REPLYlink modified 17 days ago • written 17 days ago by P Darakjian40
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