Error in saving diffmeth data

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kjfilipski • 0

@kjfilipski-16652

Last seen 5.8 years ago

Dear bioconductor team,

I am trying to use RnBeads to analyse DNA methylation data. I am especially interested in differential methylation. Unfortunately I get the following error (originally in german):

error in save.rnb.diffmeth(diffmeth, diffmeth.path) : try to call a slot "disk.dump" from an object of the simple class ("NULL") without slots

Could you please help me?

Best regards,

Katharina Filipski

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ADD COMMENT • link 5.8 years ago kjfilipski • 0

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Have you found the issue / solved the problem? We are running into the same problem.

ADD REPLY • link 4.6 years ago P Darakjian ▴ 40

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I have managed to complete the analysis once I inspected the sample annotation file for issues with tabs vs spaces. I also added the column "Sample_Name" in addition to "Sample_ID" (Sample_IDs are the names of the bed files for each sample). You also must inspect the rnb.options to make sure the identifiers.column is set to the correct column name in the sample annotation file (same thing for the covariate.adjustment.columns option).

ADD REPLY • link 4.6 years ago P Darakjian ▴ 40

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