Hi, DESeq2 error while running, please help!

Installed

conda create -y -n test.DESeq2 python=3

conda activate test.DESeq2

conda install -y bioconductor-DESeq2

To Run

$ cat counts.txt | deseq2.r 3x3 > results2.csv

ERROR Error: package or namespace load failed for 'DESeq2' in dyn.load(file, DLLpath = DLLpath, ...): unable to load shared object '/Users/xx/opt/anaconda3/envs/test.gplots/lib/R/library/DESeq2/libs/DESeq2.dylib': dlopen(/Users/xx/opt/anaconda3/envs/test.gplots/lib/R/library/DESeq2/libs/DESeq2.dylib, 6): Library not loaded: @rpath/libopenblasp-r0.3.7.dylib Referenced from: /Users/xx/opt/anaconda3/envs/test.gplots/lib/R/library/DESeq2/libs/DESeq2.dylib Reason: image not found Execution halted (test.gplots)

There is an ongoing problem with all packages that use certain libraries, the dependencies are not marked properly. Try this:

# Temporary solution on MacOS.
conda install -y libopenblas==0.3.7

See also:

• Bioconda issue: On MacOS, multiple bioconductor statistical packages use the wrong dependencies