BiocManager::install("org.Hs.eg.db")
Bioconductor version 3.8 (BiocManager 1.30.10), R 3.5.2 (2018-12-20)
Installing package(s) 'org.Hs.eg.db'
installing the source package ‘org.Hs.eg.db’

试开URL’https://bioconductor.org/packages/3.8/data/annotation/src/contrib/org.Hs.eg.db_3.7.0.tar.gz'
Content type 'application/x-gzip' length 77962833 bytes (74.4 MB)
downloaded 74.4 MB

* installing *source* package 'org.Hs.eg.db' ...
** R
** inst
** byte-compile and prepare package for lazy loading
Error: package or namespace load failed for 'AnnotationDbi' in loadNamespace(i, c(lib.loc, .libPaths()), versionCheck = vI[[i]]):
 there is no package called 'RSQLite'
Error : package 'AnnotationDbi' could not be loaded
ERROR: lazy loading failed for package 'org.Hs.eg.db'
* removing 'd:/Documents/R/win-library/3.5/org.Hs.eg.db'
In R CMD INSTALL

The downloaded source packages are in
        ‘C:\Users\Administrator\AppData\Local\Temp\RtmpmObljz\downloaded_packages’
Installation path not writeable, unable to update packages: boot, class,
  cluster, codetools, KernSmooth, lattice, MASS, Matrix, mgcv, nlme, nnet,
  rpart, spatial, survival
Old packages: 'backports', 'dplyr', 'ellipsis', 'ggforce', 'ggraph', 'glue',
  'graphlayouts', 'isoband', 'jsonlite', 'openssl', 'pkgload', 'ps',
  'RcppArmadillo', 'rlang', 'tidygraph', 'tidyr', 'tidyselect', 'vctrs'
Update all/some/none? [a/s/n]: n
Warning message:
In install.packages(...) :
  installation of package ‘org.Hs.eg.db’ had non-zero exit status

Would you please help me what is the problem for? and how can I solve it?

Thank you very much

Hello,

It might be useful if you share on which operating system you are having this error.

Anyway, although I am not completely sure, I could point out a couple things that I notice and others you could try when installing packages that are usually helpful for me.

1. To install your packages, do it from the R GUI (not RStudio) after opening it as admin; close any other instances of R that you have open (I am assuming you are on Windows).

2. It seems you need to install the RSQLite package and or AnnotationDbi before installing org.Hs.eg.db.

3. You have a version of R that is already a bit old, this shouldn't be an issue (org.Hs.eg.db requires version > 2.7) but maybe you could try updating it?

I hope this is helpful in anyway.

Best, Miguel