Dear all,

please may I ask for a suggestion regarding the algorithms to cluster the expression data in single cells at multiple time points :

we do have 10 scRNA-seq datasets that have been collected at multiple time points, and we have done :

-- the standard scRNA-seq analysis in order to identify the cluster specific markers and

-- the standard scRNA-seq analysis in order to identify the differential markers between between time points for each cell cluster

i was wondering if you could please recommend any algorithms/R package that could help with the clustering of the gene expression at different time points, per cluster of scRNA-seq. thanks a lot, and all the best,

-- bogdan